Refining the $r$-index
February 16, 2018 Β· Declared Dead Β· π Theoretical Computer Science
"No code URL or promise found in abstract"
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Authors
Hideo Bannai, Travis Gagie, Tomohiro I
arXiv ID
1802.05906
Category
cs.DS: Data Structures & Algorithms
Citations
59
Venue
Theoretical Computer Science
Last Checked
3 months ago
Abstract
Gagie, Navarro and Prezza's $r$-index (SODA, 2018) promises to speed up DNA alignment and variation calling by allowing us to index entire genomic databases, provided certain obstacles can be overcome. In this paper we first strengthen and simplify Policriti and Prezza's Toehold Lemma (DCC '16; Algorithmica, 2017), which inspired the $r$-index and plays an important role in its implementation. We then show how to update the $r$-index efficiently after adding a new genome to the database, which is likely to be vital in practice. As a by-product of this result, we obtain an online version of Policriti and Prezza's algorithm for constructing the LZ77 parse from a run-length compressed Burrows-Wheeler Transform. Our experiments demonstrate the practicality of all three of these results. Finally, we show how to augment the $r$-index such that, given a new genome and fast random access to the database, we can quickly compute the matching statistics and maximal exact matches of the new genome with respect to the database.
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