Beyond Visual Forensics: Auditing Multimodal Robustness for Synthetic Medical Image Detection

June 24, 2026 ยท Grace Period ยท ๐Ÿ› MICCAI 2026

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Authors Ching-Hao Chiu, Hao-Wei Chung, Gelei Xu, Xueyang Li, Pin-Yu Chen, John Kheir, Meysam Ghaffari, Carlos Morato, Ahmed Abbasi, Yiyu Shi arXiv ID 2606.25375 Category cs.CV: Computer Vision Cross-listed cs.AI Citations 0 Venue MICCAI 2026
Abstract
With the rapid adoption of generative AI, synthetic medical images pose growing risks, including diagnostic deception and insurance fraud. Although prior work has explored vision-language model (VLM)-based synthetic image detection, these evaluations typically consider images in isolation. In clinical practice, however, images are interpreted alongside structured records and metadata, and VLMs are increasingly deployed under joint image-record inputs. We uncover a previously underexamined multimodal vulnerability: when given both modalities, VLMs may overweight record context in authenticity judgments, such that the same image receives different predictions solely due to changes in its accompanying text. This raises concerns about robustness in real-world deployment. To systematically characterize this effect, we reformulate synthetic medical image detection as an audit of multimodal robustness at the image-record interface and introduce a paired benchmark that holds the image fixed while swapping controlled metadata variants. Across multiple imaging modalities, we evaluate diverse open-weight and frontier API VLMs and quantify how metadata alone shifts authenticity predictions. Our benchmark provides a standardized tool for assessing and improving multimodal robustness beyond image-only settings. The code is available at https://github.com/chiuhaohao/Beyond-Visual-Forensics.
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